Synergism between immunosuppressive agents and uremia?

BRIEF REPORT Primitive Neuroectodermal Tumor (PNET) of the Uterus in a Renal Allograft Patient: A Case Report

Although renal transplantation has dramatically changed the outcome of end stage renal disease, it is associated with significant side effects including opportunistic infections, graft rejection, drug toxicity, and malignancy [1]. The incidence of malignancy after renal transplant has been reported to range from 4% to 18% and may result from pre-existing cancers in recipients, donortransmitted ...

Pneumocystis and mucormycosis pneumonitis.

Two cases, one of Pneumocystis carinii pneumonia and the other of Absidia pneumonitis, are presented. Both are documented by appropriate laboratory studies. Both ended fatally in spite of seemingly appropriate current treatment. The Pneumocystis pneumonia was associated with prolonged corticosteroid therapy for progressive myositis and the Absidia infection was associated with uremia and cortic...

SDZ RAD, a new rapamycin derivative: synergism with cyclosporine.

BACKGROUND SDZ RAD is a new rapamycin analog with potent immunosuppressive activity. Compounds of the rapamycin class differ in their mode of action from cyclosporine, thus providing a rationale for potential synergism of these two potent immunosuppressants. METHODS The two-way mouse mixed lymphocyte reaction (BALB/c-CBA strain combination) was applied. Orthotopic kidney and heterotopic heart...

Medicinal Plants as Immunosuppressive Agents in Traditional Iranian Medicine

Synergism of thrombolytic agents: investigational procedures and clinical potential.

TWO PHYSIOLOGIC plasminogen activators, tissue-type plasminogen activator (t-PA) and single-chain uro-kinase-type plasminogen activator (scu-PA, prouro-kinase),' are presently under clinical investigation as fibrin-specific thrombolytic agents. Although recom-binant t-PA has been shown to be more effective and clot specific for coronary arterial thrombolysis than streptokinase, 2 3its risk/bene...